2013
2013 Jiangsu Science and Technology Award — First Prize
Biosynthesis and industrial applications of functional high-molecular-weight polyamino acids
Recipient: Chi Bo
Certificate no.: 2013-1-7-R5
RESEARCH & DEVELOPMENT
Research
Exploring regenerative materials through biosynthetic ECM.
BIOMIMETIC EXTRACELLULAR MATRIX
ECMhydro™
Biomimetic Extracellular Matrix
Biosynthetic ECM with a 3D structure.
Founder Professor Chi Bo studies biomimetic materials, focusing on biosynthetic ECM and the relationship between material structure and biological applications.
The company focuses on regenerative materials, synthetic biology and medical technology, advancing core materials research, application validation and commercialization.
Discuss technology and partnershipsRESEARCH HONORS
Research Honors
Awards associated with the team and research institutes. Recipients are identified as stated on the certificates.
2017
2017 Jiangsu Science and Technology Award — First Prize
Antitumor effects of extracellular matrix degradation products, protein engineering and applications
Recipient: High-Tech Research Institute of Nanjing University, Changzhou
Certificate no.: 2017-1-3-D2
2019.01
Ministry of Education Technological Invention Award — First Prize
Key technologies for peptide drug development and the development of innovative peptide medicines
Recipient: High-Tech Research Institute of Nanjing University, Changzhou (third contributing institution)
Certificate no.: 2018-145
2023.06
Higher Education Outstanding Scientific Research Achievement Award (Science and Technology) — First Prize for Technological Invention
Cell-membrane-inspired lipid carrier systems and their applications in transmembrane transport
Recipient: High-Tech Research Institute of Nanjing University, Changzhou
Certificate no.: 2022-283-D08
2023
6th China Medical Devices Design & Entrepreneurship Competition — First Prize in the Final
2023 China Medical Devices Design & Entrepreneurship Competition
Presented by the competition organizing committee and the National Medical Device Industry Technology Innovation Alliance
INTELLECTUAL PROPERTY
Intellectual Property & Research
Ongoing research in hydrogels and biomimetic materials.
Company Patent Applications
These documents acknowledge receipt of company patent applications. Acceptance does not mean a patent has been granted.
Invention patent application · 2025.09.19
Injectable hyaluronic acid hydrogel based on dynamic chemical bonds: preparation, applications and sol–gel transition
Application no.: 202511349196.X
Applicant: Hongbo (Changzhou) Biotechnology Co., Ltd.
Invention patent application · 2025.09.19
Self-healing hyaluronic acid–gelatin hydrogel: preparation and applications
Application no.: 202511349940.6
Applicant: Hongbo (Changzhou) Biotechnology Co., Ltd.
Team-Related Research
Representative patent literature on hydrogels, self-healing materials, antibacterial materials and biocompatible nanofibers.
PCT International Application Publication
United States Patent Certificate Cover
Antibacterial hyaluronic acid/ε-polylysine hydrogel: preparation and applications
Chinese Invention Patent Certificate 02
In-situ crosslinked poly(γ-glutamic acid) hydrogel: preparation and applications
Chinese Invention Patent Certificate 04
Bio-based self-healing hydrogel: preparation and applications
Patent Literature Directory
These 14 literature entries are transcribed from the supplied materials and include published applications and granted patent publications. Different entries may represent stages of the same application; they do not represent 14 separate granted patents. Team-related patents are not necessarily owned by Hongbo. Refer to original documents and official records for ownership and status.
- Hydrogel based on γ-polyglutamic acid and ε-polylysine crosslinked polymer, and preparation method therefor
WO2015085633A1 - ε-Polylysine hydrogel and its preparation method and application
US2003/0211129A1 - Photocrosslinked poly(γ-glutamic acid) hydrogel: preparation and applications
CN111253592B - Injectable polyamino acid hydrogel for cartilage repair and its preparation method
CN111253607A - 3D-printable antibacterial ε-polylysine hydrogel: preparation and applications
CN112111072A - In-situ crosslinked poly(γ-glutamic acid) hydrogel: preparation and applications
CN110790951B - Biomimetic antibacterial, highly adhesive double-network hydrogel: preparation and applications
CN111303452B - Antibacterial hyaluronic acid/ε-polylysine hydrogel: preparation and applications
CN112190763B - Bio-based self-healing hydrogel: preparation and applications
CN112341640B - Hydrogel based on a γ-polyglutamic acid and ε-polylysine crosslinked polymer and its preparation method
CN103656729A - Poly(γ-glutamic acid)–polyacrylonitrile composite nanofiber membrane and its preparation method
CN107354586B - Biocompatible poly(γ-glutamic acid)/polylactic acid nanofiber membrane and its preparation method
CN107460639B - Hydrogel based on a γ-polyglutamic acid and ε-polylysine crosslinked polymer and its preparation method
CN103656729B - Antibacterial ε-polylysine–p-hydroxyphenylpropionic acid hydrogel dressing and its preparation method
CN104857550B
RESEARCH DIRECTIONS
Application Exploration & Development Pipeline
Research and proof-of-concept work centered on ECM materials.
Stem cell cultureDrug deliveryTissue regeneration and repairAesthetic medicineInjectable fillers
These are materials research and application exploration areas, not approved indications for the currently registered dressing products.
DEVELOPMENT PIPELINE
Medical Devices in Development
Pilot production completed; preparing for type testing.
- Implantable absorbable gel
- Absorbable hemostatic powder
- Absorbable wound dressings